Neural interfaces for memory restoration
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Nia Therapeutics is developing neural interfaces to restore memory function after brain injury.

Memory deficits are personally devastating and represent a large unmet need. Over a million Americans currently suffer from memory loss due to traumatic brain injury.

Our technology was developed at the University of Pennsylvania with funding from DARPA and has the potential to help patients by reducing cognitive disability and increasing productivity.

How it works

  • Nia’s device continuously monitors the brain activity related to memory performance in each patient.

  • Good memory is associated with specific patterns of brain activity in temporal and frontal lobes (Burke et al 2014).

  • Targeted stimulation is delivered during poor memory states, improving memory performance by 18% (Ezzyat et al 2018)

  • Stimulation restores the brain activity associated with good memory (Ezzyat et al 2017)

 

Ezzyat et al. (2018) Nature Communications, 9:365

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Zhou et al. (2019) Nature Biomedical Engineering, 3,15–26

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Burke et al. (2014) Neuroimage, 85:834–843

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Ezzyat et al. (2017) Current Biology, 27, 1251–1258

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Press and accolades

 

New York Times

Scientific American

Brain “Pacemaker” Could Help You Remember Only What You Might Forget.

WIRED

With Strategic Zaps to the Brain, Scientists Boost Memory.

Quanta

With Strategic Zaps to the Brain, Scientists Boost Memory

New York Times

‘Pacemaker’ for the Brain Can Help Memory, Study Finds

 

 

JLABS

The JPOD, located within the University of Pennsylvania’s Pennovation Center.

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Who we are

Dan Rizzuto, PhD

Dan Rizzuto, PhD

Founder, CEO

Daniel Utin

Daniel Utin

CTO

Mike Kahana, PhD

Mike Kahana, PhD

Founder, SAB Chair

Tim Denison, PhD

Tim Denison, PhD

Advisor

Bob Gross, MD PhD

Bob Gross, MD PhD

Advisor

Bob Greenberg,  MD PhD

Bob Greenberg, MD PhD

Advisor

Ramon Diaz-Arrastia, MD PhD

Ramon Diaz-Arrastia, MD PhD

Advisor

Geoff Aguirre, MD PhD

Geoff Aguirre, MD PhD

Advisor

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